HKCV

Senior Post in the field of research and development & Managerial post

• Since completing my Ph.D. I have been involved, in the application of computers to develop a fully automated system to characterize ligands by measuring the ionization constants (pKa), affinity constants () with a range of metals and partition coefficients (Kpart). This automated system I designed has been developed to simultaneously obtain the spectrophotometric and potentiometric titration data as well as the kinetic data, where over this period of time, I have been focusing on the development and designing of novel compounds for metal chelation therapy.

• During my Ph.D. and MSc. programme, I was involved in the application of spectroscopy techniques and in particular NMR for characterising and identifying compounds under investigation in solid and in solution state. In addition, I have developed software to simulate solid state NMR spectra. Furthermore, I used the solid state NMR technique to investigate the polymorphism of the lyophilized form of phosphorus compounds.

• I have extensive experience with molecular modeling, particularly the HyperChem software release 2 for Silicon Graphics. Interested in molecular graphics (MD, MM) for understanding size and physical properties of drug delivery systems. Furthermore, I gained a considerable experience in HPLC, Drugs Formulations, TGA and DSC.

• Academic supervision
o Joint supervision of Ph.D. and M.Sc. Students.
o 1993-1996 Lotfollah Dehkordi PhD;
o 1994 - 1997 Majed Moridani PhD;
o 1995 - 1998 Zu Dong Liu PhD;
o 1997-1998 Karen Pleban (Vienna) M.Pharm; Ruth Michaelis (Frankfurt) M.Pharm.
o 1998-2000 Lubna Baydoun PhD; Feluke Fakorede PhD.; Sirivipa Piyamongkol PhD; Mutlu Aytemir ( Istanbul) Ph.D.

o 1999 - 2000 Contract work for Strakan involving the physical chemistry of zinc clindamycin phosphate complexes.
• Computing experience
o Computer programming using various languages including (Basic, Visual Basic,
o FORTRAN, Pascal).

1980 - 1981: Mathelene
Kalmoon, North Lebanon, Lebanon

1981 - 1985: BSc. Chemistry
Department of Chemistry
University of Mousel, Mousel, Iraq.

1986 - 1987 : MSc. In Chemical Spectroscopy
Thesis title : 31P NMR studies of phosphorus containing biomolecules
(Superviser Prof. G. R. Moore)
School of Chemical Sciences,
University of East Anglia, Norwich, UK.

1988 - 1992: Ph.D.
Thesis title : 1H and 31P NMR studies of small molecules and their interaction with
proteins. (Superviser Prof. G. R. Moore)
School of Chemical Sciences,
University of East Anglia, Norwich, UK.

1993 – 2003: Postdoctoral Research Fellowship
Research Topic (physical-chemical characterization of metal chelators). Pharmacy Department,
King’s College London.

2003-2005: Senior Scientist at MedPharm Company, King’s College London:
Research involved : physical-chemical characteristion of therapeutic ligands and drug formulations for different delivery systems.

November, 2006: Presenting my research interest at Qatar University, Chemistry
Department.

2006 – 2007 : A visiting Staff, CSIRO, Sydney Australia.

2008 – up to present : Self employed, and project development and design in
collaboration with the Imperial College London, Department of
Material Sciences and University of West Sydney, Australia.